Name : DR4 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9549016099
| Long name | Biotin Conjugated, DR4 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DR4 |
| Specificity | This is a highly specific antibody against DR4 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 420-468/468 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human DR4 |
| Gene ID number | 8797 |
| Swiss Prot | O00220 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Promotes the activation of NF-kappa-B, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, Receptor for the cytotoxic ligand TNFSF10/TRAIL |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | DR4 Apo2 TRAILR-1 CD261 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DR4 Conjugated |
| Short name | Conjugated, DR4 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, DR4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11904 |
| Gene | TNFRSF10A |
| Long gene name | TNF receptor superfamily member 10a |
| Synonyms gene name | member 10a , tumor necrosis factor receptor superfamily |
| Locus | 8p21, 3 |
| Discovery year | 1998-12-04 |
| GenBank acession | U90875 |
| Entrez gene record | 8797 |
| Pubmed identfication | 9311998 9082980 |
| RefSeq identity | NM_003844 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000097843 |