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DR4 Antibody, Biotin Conjugated

DR4 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, DR4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDR4
SpecificityThis is a highly specific antibody against DR4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range420-468/468
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human DR4
Gene ID number8797
Swiss ProtO00220
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Promotes the activation of NF-kappa-B, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, Receptor for the cytotoxic ligand TNFSF10/TRAIL
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DR4 Apo2 TRAILR-1 CD261
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDR4 Conjugated
Short name Conjugated, DR4 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DR4 (Antibody to)
Alternative techniqueantibodies
Identity 11904
Gene TNFRSF10A
Long gene name TNF receptor superfamily member 10a
Synonyms gene name member 10a , tumor necrosis factor receptor superfamily
Locus 8p21, 3
Discovery year 1998-12-04
GenBank acession U90875
Entrez gene record 8797
Pubmed identfication 9311998 9082980
RefSeq identity NM_003844
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000097843

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