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DR4 Antibody / Death Receptor 4

DR4 Antibody / Death Receptor 4 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDR4 / Death Receptor 4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
NotesOptimal dilution of the DR4 antibody should be determined by the researcher
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O00220
PurityAntigen affinity
Description DR4 or TRAILR1, Studies with FADD-deficient mice suggested that FADD, The protein encoded by this gene is a member of the TNF-receptor superfamily, This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), a death domain containing adaptor protein, also known as APO2, and thus transduces cell death signal and induces cell apoptosis, is a protein that in humans is encoded by the TNFRSF10A gene, is required for the apoptosis mediated by this protein, TNFRSF10A (Tumor Necrosis Factor Receptor Subfamily Member 10A)
ImmunogenAmino acids 99-131 (VLLQVVPSSAATIKLHDQSIGTQQWEHSPLGEL-human) were used as the immunogen for the DR4 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DR4 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDR4 / Death Receptor 4
Short nameDR4 Antibody / Death Receptor 4
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDR4 (Antibody to) / Death Receptor 4
Alternative techniqueantibodies
Identity 11904
Gene TNFRSF10A
Long gene name TNF receptor superfamily member 10a
Synonyms gene name member 10a , tumor necrosis factor receptor superfamily
Synonyms DR4 Apo2 TRAILR-1 CD261
Locus 8p21, 3
Discovery year 1998-12-04
GenBank acession U90875
Entrez gene record 8797
Pubmed identfication 9311998 9082980
RefSeq identity NM_003844
Classification CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT OTTHUMG00000097843

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