| Long name | DR5 Primary Polyclonal Antibody |
| Also known as | DR5 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DR5 |
| Specificity | This is a highly specific antibody against DR5 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR5/CD262 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Studies with FADD-deficient mice suggested that FADD, This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene, a death domain containing adaptor protein, and contains an intracellular death domain, and transduces an apoptosis signal, is required for the apoptosis mediated by this protein, The protein encoded by this gene is a member of the TNF-receptor superfamily |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD 262, CD262, CD262 antigen, DR 5, DR5, Death domain containing receptor for TRAIL/Apo2L, Death receptor 5, Fas like protein precursor, KILLER, KILLER/DR5, TNF related apoptosis inducing ligand receptor 2, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL R2, TRAIL receptor 2, TRAILR2, TRANCER, TRICK2, TRICK2A, TRICK2B, TRICKB, Tumor necrosis factor receptor like protein ZTNFR9, Tumor necrosis factor receptor superfamily member 10b, ZTNFR9, p53 regulated DNA damage inducible cell death receptor (killer), Death receptor 5 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DR5 |
| Short name | DR5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | DR5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11905 |
| Gene | TNFRSF10B |
| Long gene name | TNF receptor superfamily member 10b |
| Synonyms gene name | member 10b , tumor necrosis factor receptor superfamily |
| Synonyms | DR5 KILLER TRICK2A TRAIL-R2 TRICKB CD262 |
| Locus | 8p21, 3 |
| Discovery year | 1998-12-04 |
| GenBank acession | AF012628 |
| Entrez gene record | 8795 |
| Pubmed identfication | 9285725 9311998 |
| RefSeq identity | NM_147187 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000097826 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue