Name : DR5 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2214875139
| Long name | ALEXA FLUOR 488 Conjugated, DR5 Polyclonal Antibody |
| Also known as | Anti-DR5 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DR5 |
| Specificity | This is a highly specific antibody against DR5 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR5/CD262 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Studies with FADD-deficient mice suggested that FADD, This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene, a death domain containing adaptor protein, and contains an intracellular death domain, and transduces an apoptosis signal, is required for the apoptosis mediated by this protein, The protein encoded by this gene is a member of the TNF-receptor superfamily |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | DR5 KILLER TRICK2A TRAIL-R2 TRICKB CD262 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DR5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | DR5 |
| Short name | DR5 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, DR5 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11905 |
| Gene | TNFRSF10B |
| Long gene name | TNF receptor superfamily member 10b |
| Synonyms gene name | member 10b , tumor necrosis factor receptor superfamily |
| Locus | 8p21, 3 |
| Discovery year | 1998-12-04 |
| GenBank acession | AF012628 |
| Entrez gene record | 8795 |
| Pubmed identfication | 9285725 9311998 |
| RefSeq identity | NM_147187 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000097826 |