DR6 Antibody

DR6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	DR6 Primary Polyclonal Antibody
Also known as	DR6 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	DR6
Specificity	This is a highly specific antibody against DR6
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen range	140-170/655
Subcellular location	Extracellular
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR6
Gene ID number	27242
Swiss Prot	O75509
Tested Applications	FCM
Recommended dilutions	FCM(1:20-100)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm, IL10, IL13 and IFNG by Th2 cells, IL5, IgM and IgM in response to antigens, May inhibit the activation of JNK in response to T-cell stimulation, N-APP binds TNFRSF21, Negatively regulates T-cell responses and the release of cytokines such as IL4, Negatively regulates oligodendrocyte survival, Negatively regulates the production of IgG, Plays a role in neuronal apoptosis, Plays a role in signaling cascades triggered by stimulation of T-cell receptors, Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP), and is required for both normal cell body death and axonal pruning, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation, including apoptosis in response to amyloid peptides derived from APP, maturation and myelination, possibly via a pathway that involves the activation of NF-kappa-B, this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6), Promotes apoptosis
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	BM-018, CD358, Death receptor 6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21, UNQ437/PRO868, DR6
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	DR6
Short name	DR6 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	DR6 (Antibody to)
Alternative technique	antibodies
Identity	13469
Gene	TNFRSF21
Long gene name	TNF receptor superfamily member 21
Synonyms gene name	member 21 , tumor necrosis factor receptor superfamily
Synonyms	DR6 CD358
Synonyms name	death receptor 6
Locus	6p12, 3
Discovery year	2001-07-27
GenBank acession	AF068868
Entrez gene record	27242
Pubmed identfication	9714541
RefSeq identity	NM_014452
Classification	CD molecules Tumor necrosis factor receptor superfamily
Havana BLAST/BLAT	OTTHUMG00000014796

DR6 Antibody

DR6 Antibody size: 0.1ml 263

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