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DTNBP1 Antibody

DTNBP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDTNBP1 Primary Polyclonal Antibody
Also known asDTNBP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDTNBP1
SpecificityThis is a highly specific antibody against DTNBP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-180/351
Subcellular location Cytoplasm, Nucleus, Extracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DTNBP1
Gene ID number84062
Swiss ProtQ96EV8
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function, In concert with the AP-3 complex, May modulate MAPK8 phosphorylation, May play a role in actin cytoskeleton reorganization and neurite outgrowth, Modulates prefrontal cortical activity via the dopamine/D2 pathway, Plays a role in synaptic vesicle trafficking and in neurotransmitter release, Plays a role in the regulation of cell surface exposure of DRD2, Regulates the expression of SYN1 through binding to its promoter, The BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), in association with SNARE proteins, is also proposed to be involved in neurite extension, modulating PI3-kinase-Akt signaling and influencing glutamatergic release, such as platelet dense granules and melanosomes, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals, Component of the BLOC-1 complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BLOC-1 subunit 8, BLOC1S8, Biogenesis of lysosome-related organelles complex 1 subunit 8, DBND, DTNBP1, Dysbindin, Dysbindin-1, Dystrobrevin-binding protein 1, HPS7, HPS7 protein, Hermansky-Pudlak syndrome 7 protein, My031, SDY
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDTNBP1
Short nameDTNBP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDTNBP1 (Antibody to)
Alternative techniqueantibodies
Identity 17328
Gene DTNBP1
Long gene name dystrobrevin binding protein 1
Synonyms Dysbindin My031 HPS7 DBND BLOC1S8
Synonyms name dysbindin-1 biogenesis of lysosomal organelles complex-1, subunit 8
Locus 6p22, 3
Discovery year 2002-01-15
GenBank acession AF394226
Entrez gene record 84062
Pubmed identfication 11316798
RefSeq identity NM_032122
Classification Biogenesis of lysosomal organelles complex 1
Havana BLAST/BLAT OTTHUMG00000014295
Locus Specific Databases LRG_588

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