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DTNBP1 Antibody, ALEXA FLUOR 488

DTNBP1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, DTNBP1 Polyclonal Antibody
Also known asAnti-DTNBP1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDTNBP1
SpecificityThis is a highly specific antibody against DTNBP1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-180/351
Subcellular location Cytoplasm, Nucleus, Extracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DTNBP1
Gene ID Number84062
Swiss ProtQ96EV8
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function, In concert with the AP-3 complex, May modulate MAPK8 phosphorylation, May play a role in actin cytoskeleton reorganization and neurite outgrowth, Modulates prefrontal cortical activity via the dopamine/D2 pathway, Plays a role in synaptic vesicle trafficking and in neurotransmitter release, Plays a role in the regulation of cell surface exposure of DRD2, Regulates the expression of SYN1 through binding to its promoter, The BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), in association with SNARE proteins, is also proposed to be involved in neurite extension, modulating PI3-kinase-Akt signaling and influencing glutamatergic release, such as platelet dense granules and melanosomes, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals, Component of the BLOC-1 complex
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms Dysbindin My031 HPS7 DBND BLOC1S8
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DTNBP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetDTNBP1
Short nameDTNBP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, DTNBP1 (Antibody to)
Alternative techniqueantibodies
Identity 17328
Gene DTNBP1
Long gene name dystrobrevin binding protein 1
Synonyms name dysbindin-1 biogenesis of lysosomal organelles complex-1, subunit 8
Locus 6p22, 3
Discovery year 2002-01-15
GenBank acession AF394226
Entrez gene record 84062
Pubmed identfication 11316798
RefSeq identity NM_032122
Classification Biogenesis of lysosomal organelles complex 1
Havana BLAST/BLAT OTTHUMG00000014295
Locus Specific Databases LRG_588

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