Name : DTNBP1 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9744963420
| Long name | ALEXA FLUOR 647 Conjugated, DTNBP1 Polyclonal Antibody |
| Also known as | Anti-DTNBP1 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DTNBP1 |
| Specificity | This is a highly specific antibody against DTNBP1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-180/351 |
| Subcellular location | Cytoplasm, Nucleus, Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DTNBP1 |
| Gene ID Number | 84062 |
| Swiss Prot | Q96EV8 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function, In concert with the AP-3 complex, May modulate MAPK8 phosphorylation, May play a role in actin cytoskeleton reorganization and neurite outgrowth, Modulates prefrontal cortical activity via the dopamine/D2 pathway, Plays a role in synaptic vesicle trafficking and in neurotransmitter release, Plays a role in the regulation of cell surface exposure of DRD2, Regulates the expression of SYN1 through binding to its promoter, The BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), in association with SNARE proteins, is also proposed to be involved in neurite extension, modulating PI3-kinase-Akt signaling and influencing glutamatergic release, such as platelet dense granules and melanosomes, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals, Component of the BLOC-1 complex |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | Dysbindin My031 HPS7 DBND BLOC1S8 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the DTNBP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | DTNBP1 |
| Short name | DTNBP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, DTNBP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17328 |
| Gene | DTNBP1 |
| Long gene name | dystrobrevin binding protein 1 |
| Synonyms name | dysbindin-1 biogenesis of lysosomal organelles complex-1, subunit 8 |
| Locus | 6p22, 3 |
| Discovery year | 2002-01-15 |
| GenBank acession | AF394226 |
| Entrez gene record | 84062 |
| Pubmed identfication | 11316798 |
| RefSeq identity | NM_032122 |
| Classification | Biogenesis of lysosomal organelles complex 1 |
| Havana BLAST/BLAT | OTTHUMG00000014295 |
| Locus Specific Databases | LRG_588 |