Name : DTX2 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3415351075
| Long name | FITC Conjugated, DTX2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DTX2 |
| Specificity | This is a highly specific antibody against DTX2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human DTX2 |
| Gene ID number | 113878 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | DTX2 also functions as an ubiquitin ligase protein in vitro, DTX2 is a regulator of Notch signaling, It contains one RING-type zinc finger and two WWE domains, It probably acts both as a positive and negative regulator of Notch, The WWE domains are thought to mediate some protein-protein interaction, There are two named isoforms, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations, and are frequently found in ubiquitin ligases, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity, DTX2 belongs to the Deltex family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | RNF58 KIAA1528 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DTX2 Conjugated |
| Short name | FITC Conjugated, DTX2 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, DTX2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 15973 |
| Gene | DTX2 |
| Long gene name | deltex E3 ubiquitin ligase 2 |
| Synonyms gene name | E3 ubiquitin ligase , deltex (Drosophila) homolog 2 deltex homolog 2 (Drosophila) deltex 2 |
| Locus | 7q11, 23 |
| Discovery year | 2001-08-13 |
| Entrez gene record | 113878 |
| Pubmed identfication | 12670957 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000162594 |