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DUOX1 Antibody

DUOX1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDUOX1 Primary Polyclonal Antibody
Also known asDUOX1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDUOX1
SpecificityThis is a highly specific antibody against DUOX1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUOX1
Gene ID number53905
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DUOX1, DUOX1 generates hydrogen peroxide, DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa, a homolog of glycoprotein p91Phox, as well as thyroid, is expressed in airway epithelium and generates reactive oxygen species (ROS), is widely expressed in fetal tissues, trachea and bronchium, which also plays a role in mucin expression, which is crucial for thyroid peroxidase and lactoperoxidase, Dual oxidase 1 (DUOX1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DUOX1, DUOX1_HUMAN, Dual oxidase 1 precursor, EC 1, EC 1, Flavoprotein NADPH oxidase, LNOX1, Large NOX 1, Long NOX 1, MGC138840, MGC138841, NADPH thyroid oxidase 1, NOXEF1, Nicotinamide adenine dinucleotide phosphate oxidase, THOX1, Thyroid oxidase 1, 1, 1, 3, 6, 11, Dual oxidase 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDUOX1
Short nameDUOX1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namedual oxidase 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DUOX1 and IDBG-10154 and ENSG00000137857 and 53905, DUOX1 and IDBG-646697 and ENSBTAG00000016246 and 510409, Duox1 and IDBG-202931 and ENSMUSG00000033268 and 99439, NADP binding, Plasma membranes, this GO :0004601 and peroxidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006590 and thyroid hormone generation and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016174 and NAD(P)H oxidase activity and molecular function this GO :0016324 and apical plasma membrane and cellular component this GO :0016491 and oxidoreductase activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0020037 and heme binding and molecular function this GO :0042335 and cuticle development and biological process this GO :0042446 and hormone biosynthetic process and biological process this GO :0042554 and superoxide anion generation and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050661 and NADP binding and molecular function this GO :0050665 and hydrogen peroxide biosynthetic process and biological process this GO :0051591 and response to cAMP and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process, this GO :0004601: peroxidase activity, this GO :0004601: peroxidase activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0016174: NAD(P)H oxidase activity and also this GO :0016491: oxidoreductase activity and also this GO :0020037: heme binding and also this GO :0050661: NADP binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0016174: NAD(P)H oxidase activity, this GO :0016491: oxidoreductase activity, this GO :0020037: heme binding, this GO :0050661: NADP binding, dual oxidase 1
Identity 3062
Gene DUOX1
Long gene name dual oxidase 1
Synonyms NOXEF1 THOX1 LNOX1
Synonyms name NADPH thyroid oxidase 1 flavoprotein NADPH oxidase nicotinamide adenine dinucleotide phosphate oxidase
Locus 15q21, 1
Discovery year 2000-05-30
GenBank acession AF213465
Entrez gene record 53905
Pubmed identfication 10806195
RefSeq identity NM_017434
Classification EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000171987

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