Name : DUOXA2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1334663369
| Long name | Biotin Conjugated, DUOXA2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | DUOXA2 |
| Specificity | This is a highly specific antibody against DUOXA2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human DUOXA2 |
| Gene ID number | 405753 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Angelman syndrome, DUOXA2 is essential for the maturation and transport of DUOX2 from the ER to the plasma membrane and is also thought to play a role in the synthesis of thyroid hormone (TH), Defects in the DUOXA2 gene are associated with the pathogenesis of congenital hypothyroidism, Expressed specifically in thyroid and salivary glands, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes, The gene encoding DUOXA2 maps to human chromosome 15, a disorder that affects infants and is characterized by a significant decrease or a complete deficiency of TH from birth, which houses over 700 genes and comprises nearly 3% of the human genome, DUOXA2 is a 320 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum (ER) and belongs to the DUOXA family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DUOXA2 Conjugated |
| Short name | Conjugated, DUOXA2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, DUOXA2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 32698 |
| Gene | DUOXA2 |
| Long gene name | dual oxidase maturation factor 2 |
| Locus | 15q21, 1 |
| Discovery year | 2006-05-16 |
| GenBank acession | BX537581 |
| Entrez gene record | 405753 |
| Pubmed identfication | 16651268 |
| RefSeq identity | NM_207581 |
| Havana BLAST/BLAT | OTTHUMG00000131354 |