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DUSP1 Antibody

DUSP1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDUSP1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB
Recommended dilutionsImmunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the DUSP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis DUSP1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P28562
PurityPurified
Description DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation, Furthermore, It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, Thus, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes, The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors
ImmunogenA portion of amino acids 46-76 from the human protein was used as the immunogen for this DUSP1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the DUSP1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDUSP1
Short nameDUSP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namedual specificity phosphatase 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, CL100 and HVH1 and MKP-1 and MKP1 and PTPN10, DUSP1 and IDBG-57812 and ENSG00000120129 and 1843, Dusp1 and IDBG-155234 and ENSMUSG00000024190 and 19252, MAP kinase tyrosine/serine/threonine phosphatase activity, nuclei, this GO :0000188 and inactivation of MAPK activity and biological process this GO :0001706 and endoderm formation and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0004726 and non-membrane spanning protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0008330 and protein tyrosine/threonine phosphatase activity and molecular function this GO :0009416 and response to light stimulus and biological process this GO :0010033 and response to organic substance and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017017 and MAP kinase tyrosine/serine/threonine phosphatase activity and molecular function this GO :0032355 and response to estradiol and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0033574 and response to testosterone and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035970 and peptidyl-threonine dephosphorylation and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051447 and negative regulation of meiotic cell cycle and biological process this GO :0051591 and response to cAMP and biological process this GO :0051592 and response to calcium ion and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0071850 and mitotic cell cycle arrest and biological process this GO :0090266 and regulation of mitotic cell cycle spindle assembly checkpoint and biological process this GO :2000279 and negative regulation of DNA biosynthetic process and biological process, this GO :0004725: protein tyrosine phosphatase activity, this GO :0004725: protein tyrosine phosphatase activity and also this GO :0004726: non-membrane spanning protein tyrosine phosphatase activity and also this GO :0005515: protein binding and also this GO :0008138: protein tyrosine/serine/threonine phosphatase activity and also this GO :0008330: protein tyrosine/threonine phosphatase activity and also this GO :0016791: phosphatase activity and also this GO :0017017: MAP kinase tyrosine/serine/threonine phosphatase activity, this GO :0004726: non-membrane spanning protein tyrosine phosphatase activity, this GO :0005515: protein binding, this GO :0008138: protein tyrosine/serine/threonine phosphatase activity, this GO :0008330: protein tyrosine/threonine phosphatase activity, this GO :0016791: phosphatase activity, this GO :0017017: MAP kinase tyrosine/serine/threonine phosphatase activity, 85182 and IDBG-628495 and ENSBTAG00000013863 and 539175, dual specificity phosphatase 1
Identity 3067
Gene DUSP12
Long gene name dual specificity phosphatase 12
Synonyms YVH1 DUSP1
Synonyms name cerevisiae) ortholog , serine/threonine specific protein phosphatase YVH1 protein-tyrosine phosphatase (S
Locus 1q23, 3
Discovery year 2000-01-31
GenBank acession AF119226
Entrez gene record 11266
Pubmed identfication 10446167
RefSeq identity NM_007240
Classification Atypical dual specificity phosphatases
Havana BLAST/BLAT OTTHUMG00000034540

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