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DUSP3 Antibody, HRP Conjugated

DUSP3 Antibody, HRP Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name HRP Conjugated, DUSP3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDUSP3
SpecificityThis is a highly specific antibody against DUSP3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DUSP3
Gene ID number1845
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Although DUSP3 is expressed in both breast and ovarian tissues, Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, SAPK/JNK, These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues, They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer, and different modes of inducibility of their expression by extracellular stimuli, different tissue distribution and subcellular localization, leading to the conclusion that this gene is not BRCA1, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, p38), which are associated with cellular proliferation and differentiation, The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetDUSP3 Conjugated
Short name Conjugated, DUSP3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name horseradish peroxidase coupled, dual specificity phosphatase 3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DUSP3 and IDBG-52945 and ENSG00000108861 and 1845, DUSP3 and IDBG-640759 and ENSBTAG00000003966 and 615432, Dusp3 and IDBG-212400 and ENSMUSG00000003518 and 72349, MAP kinase phosphatase activity, VHR, nuclei, this GO :0000188 and inactivation of MAPK activity and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001772 and immunological synapse and cellular component this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004721 and phosphoprotein phosphatase activity and molecular function this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0008138 and protein tyrosine/serine/threonine phosphatase activity and molecular function this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0033549 and MAP kinase phosphatase activity and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045931 and positive regulation of mitotic cell cycle and biological process this GO :0046329 and negative regulation of JNK cascade and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050860 and negative regulation of T cell receptor signaling pathway and biological process this GO :0050868 and negative regulation of T cell activation and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process, this GO :0004721: phosphoprotein phosphatase activity, this GO :0004721: phosphoprotein phosphatase activity and also this GO :0004725: protein tyrosine phosphatase activity and also this GO :0008138: protein tyrosine/serine/threonine phosphatase activity and also this GO :0016791: phosphatase activity and also this GO :0033549: MAP kinase phosphatase activity, this GO :0004725: protein tyrosine phosphatase activity, this GO :0008138: protein tyrosine/serine/threonine phosphatase activity, this GO :0016791: phosphatase activity, this GO :0033549: MAP kinase phosphatase activity, dual specificity phosphatase 3
Identity 3069
Gene DUSP3
Long gene name dual specificity phosphatase 3
Synonyms gene VHR
Synonyms gene name vaccinia virus phosphatase VH1-related
Locus 17q21, 31
Discovery year 1994-05-19
GenBank acession BC035701
Entrez gene record 1845
Pubmed identfication 7829094
RefSeq identity NM_004090
Classification Atypical dual specificity phosphatases
Havana BLAST/BLAT OTTHUMG00000180889

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