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DVL2 (Thr224) Antibody, Biotin Conjugated

DVL2 (Thr224) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DVL2 (Thr224) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDVL2 Thr224
Specificity This antibody will recognize DVL3 when phosphorylated at Thr205, This is a highly specific antibody against DVL2 Thr224
ModificationPhosphorylation
Modification siteThr224
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range200-250/736
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224
Gene ID number1856
Swiss ProtO14641
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity), Promotes internalization and degradation of frizzled proteins upon Wnt signaling, Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDVL2 (Thr224) Conjugated
Short name Conjugated, DVL2 (Thr224) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, DVL2 (Thr224) (Antibody to)
Alternative techniqueantibodies
Identity 3086
Gene DVL2
Long gene name dishevelled segment polarity protein 2
Synonyms gene name dishevelled 2 (homologous to Drosophila dsh) dishevelled, dsh homolog 2 (Drosophila)
Locus 17p13, 1
Discovery year 1996-03-12
GenBank acession BC014844
Entrez gene record 1856
Pubmed identfication 8662242
RefSeq identity NM_004422
Classification Dishevelled segment polarity proteins PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000102155

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