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DVL2 (Thr224) Antibody, FITC Conjugated

DVL2 (Thr224) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, DVL2 (Thr224) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDVL2 Thr224
Specificity This antibody will recognize DVL3 when phosphorylated at Thr205, This is a highly specific antibody against DVL2 Thr224
ModificationPhosphorylation
Modification siteThr224
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range200-250/736
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224
Gene ID number1856
Swiss ProtO14641
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity), Promotes internalization and degradation of frizzled proteins upon Wnt signaling, Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDVL2 (Thr224) Conjugated
Short name FITC Conjugated, DVL2 (Thr224) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, DVL2 (Thr224) (Antibody to)
Alternative techniqueantibodies
Identity 3086
Gene DVL2
Long gene name dishevelled segment polarity protein 2
Synonyms gene name dishevelled 2 (homologous to Drosophila dsh) dishevelled, dsh homolog 2 (Drosophila)
Locus 17p13, 1
Discovery year 1996-03-12
GenBank acession BC014844
Entrez gene record 1856
Pubmed identfication 8662242
RefSeq identity NM_004422
Classification Dishevelled segment polarity proteins PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000102155

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