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DYRK1A Antibody

DYRK1A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDYRK1A Primary Polyclonal Antibody
Also known asDYRK1A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDYRK1A
SpecificityThis is a highly specific antibody against DYRK1A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DYRK1A
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Dyrk family members, Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, Dyrk1A, Dyrk1A is a candidate gene for learning defects that are involved in Downs syndrome (DS), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, Four isoforms of Dyrk1A exist due to alternative splicing events, Localized to the nucleus and highly expressed in testis, Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases, also known as MNB or MNBH, are thought to be involved in diverse cellular functions, functions to phosphorylate serine, including Dyrk1A (dual specificity tyrosine-phosphorylation-regulated kinase 1A), muscle and the developing nervous system, suggesting a possible role for Dyrk1A in the development of DS, threonine and tyrosine residues on various substrates involved in signaling pathways that regulate cell proliferation, which is itself regulated by tyrosine phosphorylation, Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene which is required for neurogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DYR1A_HUMAN, DYRK , DYRK 1, DYRK 1A, DYRK1 , DYRKA, HP 86, HP86, MNB , MNB/DYRK protein kinase antibody, MNBH, Minibrain Drosophila homolog, Minibrain homolog, Protein kinase minibrain homolog, Serine/threonine kinase MNB, Dual specicity tyrosine phosphorylation regulated kinase 1A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDYRK1A
Short nameDYRK1A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDYRK1A (Antibody to)
Alternative techniqueantibodies
Identity 3091
Gene DYRK1A
Long gene name dual specificity tyrosine phosphorylation regulated kinase 1A
Synonyms gene DYRK1 DYRK MNBH
Synonyms gene name dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
Locus 21q22, 13
Discovery year 1999-01-29
GenBank acession U52373
Entrez gene record 1859
Pubmed identfication 9284911
RefSeq identity NM_001396
Havana BLAST/BLAT OTTHUMG00000086657

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