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DYRK1A Antibody, ALEXA FLUOR 594

DYRK1A Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, DYRK1A Polyclonal Antibody
Also known asAnti-DYRK1A PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDYRK1A
SpecificityThis is a highly specific antibody against DYRK1A
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DYRK1A
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Dyrk family members, Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, Dyrk1A, Dyrk1A is a candidate gene for learning defects that are involved in Downs syndrome (DS), Dyrk1B, Dyrk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, Four isoforms of Dyrk1A exist due to alternative splicing events, Localized to the nucleus and highly expressed in testis, Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases, also known as MNB or MNBH, are thought to be involved in diverse cellular functions, functions to phosphorylate serine, including Dyrk1A (dual specificity tyrosine-phosphorylation-regulated kinase 1A), muscle and the developing nervous system, suggesting a possible role for Dyrk1A in the development of DS, threonine and tyrosine residues on various substrates involved in signaling pathways that regulate cell proliferation, which is itself regulated by tyrosine phosphorylation, Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene which is required for neurogenesis
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetDYRK1A
Short nameDYRK1A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, DYRK1A (Antibody to)
Alternative techniqueantibodies
Identity 3091
Gene DYRK1A
Long gene name dual specificity tyrosine phosphorylation regulated kinase 1A
Synonyms gene DYRK1 DYRK MNBH
Synonyms gene name dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
Locus 21q22, 13
Discovery year 1999-01-29
GenBank acession U52373
Entrez gene record 1859
Pubmed identfication 9284911
RefSeq identity NM_001396
Havana BLAST/BLAT OTTHUMG00000086657

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