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DYRK2 Antibody, Biotin Conjugated

DYRK2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, DYRK2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDYRK2
SpecificityThis is a highly specific antibody against DYRK2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human DYRK2
Gene ID number8445
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Dryk1C, Dyrk family members, Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, Dyrk1A is a candidate gene that may be involved in Downs syndrome, Dyrk1B, Dyrk2, Dyrk3, Dyrk3 is strongly expressed in testis, Dyrk4A and Dyrk4B, Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4), The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4), and it has been found to be somewhat overexpressed in Downs syndrome (1, and very weakly expressed in spleen and adrenal gland (1), are thought to be involved in diverse cellular functions (4), including Dyrk1A (originally Dyrk), only after the onset of spermatogenesis, respectively (4), which is itself regulated by tyrosine phosphorylation (1), which is required for neurogenesis (1â, &euro, &ldquo, 3), 5), Dyrk is the homolog of the Drosophila mnb (minibrain) gene
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetDYRK2 Conjugated
Short name Conjugated, DYRK2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DYRK2 and IDBG-45841 and ENSG00000127334 and 8445, DYRK2 and IDBG-634243 and ENSBTAG00000007256 and 514916, Dyrk2 and IDBG-192216 and ENSMUSG00000028630 and 69181, nuclei, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0000287 and magnesium ion binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004712: protein serine/threonine/tyrosine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004712: protein serine/threonine/tyrosine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0030145: manganese ion binding, this GO :0043130: ubiquitin binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030145: manganese ion binding and also this GO :0043130: ubiquitin binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030145 and manganese ion binding and molecular function this GO :0030529 and ribonucleoprotein complex and cellular component this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0051534 and negative regulation of NFAT protein import into nucleus and biological process, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Identity 3093
Gene DYRK2
Long gene name dual specificity tyrosine phosphorylation regulated kinase 2
Synonyms gene name dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 dual specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Locus 12q15
Discovery year 1998-10-29
GenBank acession Y09216
Entrez gene record 8445
Pubmed identfication 9748265
Havana BLAST/BLAT OTTHUMG00000169089

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