Name : Dysadherin Antibody
Supplier : NJS POLY
Price :389
SKU : GEN3520791894
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Dysadherin |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the Dysadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Dysadherin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q96DB9 |
| Purity | Antigen affinity |
| Description | Dysadherin expression was significantly higher in undifferentiated carcinoma than in papillary carcinoma or follicular carcinoma and showed significant negative correlation with E-cadherin expression, Immunoreactivity for Dysadherin, The FXYD5 gene is mapped on 19q13, The deduced FXYD5 protein, The gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, also known as Dysadherin, beginning with the sequence 'PFXYD' and containing 7 invariant and 6 highly conserved amino acids, contains 178 amino acids and has a signal peptide, is a protein that in humans is encoded by the FXYD5 gene, localized at cell-cell boundaries, the largest of the 7, was detected in 39 of 51 papillary carcinomas and in all 31 undifferentiated carcinomas but not in the follicular carcinomas or normal thyroid tissue controls, 12, FXYD5 (FXYD domain-containing ion transport regulator 5) |
| Immunogen | An amino acid sequence from the C-terminus of human FXYD5/Dysadherin (KCRQLSRLCRNRCR) was used as the immunogen for this Dysadherin antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Dysadherin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Dysadherin |
| Short name | Dysadherin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Dysadherin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4029 |
| Gene | FXYD5 |
| Long gene name | FXYD domain containing ion transport regulator 5 |
| Synonyms gene name | FXYD domain-containing ion transport regulator 5 |
| Synonyms | OIT2 |
| Synonyms name | dysadherin |
| Locus | 19q13, 12 |
| Discovery year | 2000-05-23 |
| GenBank acession | AF161462 |
| Entrez gene record | 53827 |
| RefSeq identity | NM_014164 |
| Havana BLAST/BLAT | OTTHUMG00000048092 |