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Dyskerin Antibody, ALEXA FLUOR 488

Dyskerin Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Dyskerin Polyclonal Antibody
Also known asAnti-Dyskerin PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDyskerin
SpecificityThis is a highly specific antibody against Dyskerin
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dyskerin
Gene ID Number1736
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen DKC is a rare, GAR1, Missense mutations in the dyskerin gene interfere with normal nuclear localization of dyskerin and cause Dyskeratosis congenita (DKC) (4), NHP2 (NOLA2) and Nop10 for the isomerization of uridine to pseudouridine (1), NHP2 and dyskerin localize to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies (2), The GAR1 gene maps to chromosome 4q25 (5, The NHP2 gene maps to chromosome 5q35, The dyskerin gene maps to chromosome Xq28 (3), X-linked bone marrow disorder characterized by cutaneous hyperpigmentation, atrophy of the testicles and leukoplakia of the oral mucosa, dystrophy of the nails, 3 and encodes a 155-amino acid protein (2, 6), 7), Dyskerin (NAP57) associates with the chaperone protein Nopp140 and forms a small ribonucleoprotein particle with GAR1 (NOLA1)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms XAP101 dyskerin NAP57 NOLA4 Cbf5
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Dyskerin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetDyskerin
Short nameDyskerin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Dyskerin (Antibody to)
Alternative techniqueantibodies
Identity 2890
Gene DKC1
Long gene name dyskerin pseudouridine synthase 1
Synonyms gene DKC
Synonyms gene name dyskeratosis congenita 1, dyskerin
Synonyms name H/ACA ribonucleoprotein complex subunit 4
Locus Xq28
Discovery year 2001-06-22
GenBank acession AJ224481
Entrez gene record 1736
Pubmed identfication 9590285 9888995
RefSeq identity NM_001363
Classification H/ACA ribonucleoprotein complex
Havana BLAST/BLAT OTTHUMG00000024242
Locus Specific Databases DKC1base: Mutation registry for Hoyeraal-Hreidarsson syndrome Mental Retardation database LRG_55

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