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Dyskerin Antibody, Cy7 Conjugated

Dyskerin Antibody, Cy7 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy7 Conjugated, Dyskerin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenDyskerin
SpecificityThis is a highly specific antibody against Dyskerin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Dyskerin
Gene ID number1736
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DKC is a rare, GAR1, Missense mutations in the dyskerin gene interfere with normal nuclear localization of dyskerin and cause Dyskeratosis congenita (DKC) (4), NHP2 (NOLA2) and Nop10 for the isomerization of uridine to pseudouridine (1), NHP2 and dyskerin localize to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies (2), The GAR1 gene maps to chromosome 4q25 (5, The NHP2 gene maps to chromosome 5q35, The dyskerin gene maps to chromosome Xq28 (3), X-linked bone marrow disorder characterized by cutaneous hyperpigmentation, atrophy of the testicles and leukoplakia of the oral mucosa, dystrophy of the nails, 3 and encodes a 155-amino acid protein (2, 6), 7), Dyskerin (NAP57) associates with the chaperone protein Nopp140 and forms a small ribonucleoprotein particle with GAR1 (NOLA1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms CBF5 homolog, Cbf5p homolog, DKC, DKC 1, DKC1_HUMAN, DKCX, Dkc1, Dyskeratosis congenita 1, Dyskeratosis congenita 1 dyskerin, Dyskerin, H/ACA ribonucleoprotein complex subunit 4, NAP 57, NAP-57, NAP57, NOLA 4, NOLA4, Nopp140 associated protein of 57 kDa, Nopp140-associated protein of 57 kDa, Nucleolar protein NAP57, Nucleolar protein family A member 4, XAP 101, XAP101, snoRNP protein DKC1, CBF5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetDyskerin Conjugated
Short name Conjugated, Dyskerin Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, Dyskerin (Antibody to)
Alternative techniqueantibodies

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