Filters

DYT1 (583CT1.1.3) Monoclonal Antibody

DYT1 (583CT1.1.3) Monoclonal Antibody size: 0.1ml 328

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 328
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1, 3) Monoclonal Antibody, DYT1 (583CT1
Also known as1, 3) Monoclonal Antibody, DYT1 (583CT1
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDYT1
SpecificityThis is a highly specific antibody against DYT1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 3, 583CT1
SourcePurified His-tagged DYT1 protein(Fragment) was used to produced this monoclonal antibody
Gene ID number1861
Swiss ProtO14656
Tested ApplicationsWB
Recommended dilutionsWB(1:1000-5000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In the endoplasmic reticulum, In the nucleus, Involved in the regulation of synaptic vesicle recycling, May have a redundant function with TOR1B in non-neural tissues, Participates in the cellular trafficking and may regulate the subcellular location of multipass membrane proteins such as the dopamine transporter SLC6A3, cell movement and, controls STON2 protein stability in collaboration with the COP9 signalosome complex (CSN), leading to the modulation of dopamine neurotransmission, may link the cytoskeleton with the nuclear envelope, nuclear envelope integrity, plays a role in the quality control of protein folding by increasing clearance of misfolded proteins such as SGCE variants or holding them in an intermediate state for proper refolding, processing, specifically in neurons, stability and localization as well as for the reduction of misfolded protein aggregates, this mechanism seems to be crucial for the control of nuclear polarity, Protein with chaperone functions important for the control of protein folding
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DYT1, Dystonia 1 protein, TA, TOR1A, TORA, Torsin ATPase-1A, Torsin family 1 member A, Torsin-1A, DQ2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1, 3) Monoclonal, DYT1 (583CT1
Short name1, 3) Monoclonal Antibody, DYT1 (583CT1
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1, 3) monoclonal (Antibody to), DYT1 (583CT1
Alternative techniqueantibodies
Identity 3098
Gene TOR1A
Long gene name torsin family 1 member A
Synonyms gene DYT1
Synonyms gene name dystonia 1, member A (torsin A) , torsin A) torsin family 1, torsion (autosomal dominant
Synonyms DQ2
Synonyms name torsin A
Locus 9q34, 11
Discovery year 1987-09-11
GenBank acession AF007871
Entrez gene record 1861
Pubmed identfication 10644435
RefSeq identity NM_000113
Havana BLAST/BLAT OTTHUMG00000020794
Locus Specific Databases LRG_1029

Similar products

Subscribe to our Newsletter