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Ecadherin binding protein E7 Antibody

Ecadherin binding protein E7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEcadherin binding protein E7 Antibody
Also known asEcadherin binding protein E7 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEcadherin binding protein E7
SpecificityThis is a highly specific antibody against Ecadherin binding protein E7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CBLL1/Ecadherin binding protein E7
Gene ID number79872
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions, More specifically, Via its role as an E-cadherin regulator, also known as HAKAI (meaning â, in Japanese), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger, or RNF188 (RING finger protein 188), thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts, upon activation of c-Src, &euro, &euro, &tilde, &trade, CBLL1, destructionâ
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CasBrM murine ecotropic retroviral transforming sequencelike 1, Casitas B-lineage lymphoma transforming sequence-like protein 1, Casitas B-lineage lymphoma-like 1, Casitas B-lineage lymphoma-transforming sequence-like protein 1, E3 ubiquitin-protein ligase Hakai, Ecadherin binding protein E7, FLJ23109, HAKAI, HAKAI_HUMAN, MGC163401, MGC163403, OTTHUMP00000206720, OTTHUMP00000206722, OTTHUMP00000206724, RING finger protein 188, RNF188, cbll1, c-Cbl-like protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEcadherin binding protein E7
Short nameEcadherin binding protein E7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEcadherin binding protein E7 (Antibody to)
Alternative techniqueantibodies

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