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Ecadherin binding protein E7 Antibody, Biotin Conjugated

Ecadherin binding protein E7 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Ecadherin binding protein E7 Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEcadherin binding protein E7
SpecificityThis is a highly specific antibody against Ecadherin binding protein E7
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human CBLL1/Ecadherin binding protein E7
Gene ID number79872
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background CBLL1 interacts with and ubiquitinates tyrosine-phosphorylated E-cadherin, CBLL1 is believed to function as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation, CBLL1 participates in cell adhesion and may also be involved in the regulation of epithelial-mesenchymal transitions, More specifically, Via its role as an E-cadherin regulator, also known as HAKAI (meaning â, in Japanese), is a 491 amino acid protein that contains one C2H2-type zinc finger and one RING-type zinc finger, or RNF188 (RING finger protein 188), thereby targeting the E-cadherin complex for endocytosis and disrupting epithelial cell-cell contacts, upon activation of c-Src, &euro, &euro, &tilde, &trade, CBLL1, destructionâ
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CasBrM murine ecotropic retroviral transforming sequencelike 1, Casitas B-lineage lymphoma transforming sequence-like protein 1, Casitas B-lineage lymphoma-like 1, Casitas B-lineage lymphoma-transforming sequence-like protein 1, E3 ubiquitin-protein ligase Hakai, Ecadherin binding protein E7, FLJ23109, HAKAI, HAKAI_HUMAN, MGC163401, MGC163403, OTTHUMP00000206720, OTTHUMP00000206722, OTTHUMP00000206724, RING finger protein 188, RNF188, cbll1, c-Cbl-like protein 1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEcadherin binding protein E7 Conjugated
Short name Conjugated, Ecadherin binding protein E7 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Ecadherin binding protein E7 (Antibody to)
Alternative techniqueantibodies

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