Name : EFS Antibody / Embryonal Fyn-associated substrate
Supplier : NJS POLY
Price :199
SKU : GEN7156602062
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | EFS / Embryonal Fyn-associated substrate |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | Western blot: 1:1000-1:2000 |
| Intented use | This EFS antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 10278 |
| Uniprot # | O43281 |
| Purity | Antigen affinity |
| Description | Interacts with the SH3 domain of FYN and with CRK, May serve as an activator of SRC and a downstream effector, SRC, and YES (By similarity), Embryonal Fyn-associated substrate is a docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion |
| Immunogen | A portion of amino acids 367-399 from the human protein was used as the immunogen for the EFS antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the EFS antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | EFS / Embryonal Fyn-associated substrate |
| Short name | EFS Antibody / Embryonal Fyn-associated substrate |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FGR, FGR, YES-associated substrate, YES-associated substrate (Antibody to) / Embryonal FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), embryonal FYN oncogene related to v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) |
| Alternative technique | antibodies |
| Alternative to gene target | CAS3 and CASS3 and EFS1 and EFS2 and HEFS and SIN, Cytoplasm, EFS and IDBG-3201 and ENSG00000100842 and 10278, EFS and IDBG-645821 and ENSBTAG00000038733 and 508559, Efs and IDBG-162509 and ENSMUSG00000022203 and 13644, protein domain specific binding, this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0035556 and intracellular signal transduction and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding and also this GO :0019904: protein domain specific binding, this GO :0017124: SH3 domain binding, this GO :0019904: protein domain specific binding, embryonal Fyn-associated substrate |
| Identity | 16898 |
| Gene | EFS |
| Long gene name | embryonal Fyn-associated substrate |
| Synonyms | EFS2 EFS1 HEFS SIN CASS3 |
| Synonyms name | Cas scaffolding protein family member 3 |
| Locus | 14q11, 2 |
| Discovery year | 2003-01-29 |
| GenBank acession | AB001466 |
| Entrez gene record | 10278 |
| Pubmed identfication | 9349509 |
| Classification | Cas scaffolding proteins |
| Havana BLAST/BLAT | OTTHUMG00000028741 |