| Long name | eIF4E Primary Polyclonal Antibody |
| Also known as | eIF4E PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | e4E |
| Specificity | This is a highly specific antibody against e4E |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human eIF4E |
| Gene ID number | 1977 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Phosphorylation also enhances the interaction of eIF4E with eIF4G, Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA, Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription, eIF4E also influences the overall rate of translation, eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs, eIF4E phosphorylation is correlated with increased translational rate in a number of cell types, which form a complex known as eIF4F, eIF4E |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CBP, CBP, E 4F, E4E1, E4EL1, E4F, Eukaryotic Translation Initiation Factor 4 E, Eukaryotic translation initiation factor 4E like 1, Messanger RNA Cap Binding Protein e 4E, e 4E, e 4E, e 4F 25 kDa subunit, e 4F 25 kDa subunit, e-4E, E4F |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | eIF4E |
| Short name | eIF4E Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | eIF4E (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3287 |
| Gene | EIF4E |
| Long gene name | eukaryotic translation initiation factor 4E |
| Synonyms gene | EIF4EL1 EIF4F |
| Synonyms | EIF4E1 |
| Locus | 4q23 |
| Discovery year | 1991-07-09 |
| GenBank acession | M15353 |
| Entrez gene record | 1977 |
| Pubmed identfication | 9330633 1916814 |
| RefSeq identity | NM_001968 |
| Havana BLAST/BLAT | OTTHUMG00000161090 |
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