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EIF4G1 (Ser1238) Antibody

EIF4G1 (Ser1238) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEIF4G1 (Ser1238) Primary Polyclonal Antibody
Also known asEIF4G1 (Ser1238) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenE4G1 Ser1238
SpecificityThis is a highly specific antibody against E4G1 Ser1238
Modification(s)Phosphorylation
Modification site(s)Ser1238
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human EIF4G1 around the phosphorylation site of Ser1238
Gene ID number1981
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A domain at its N-terminus can also interact with the poly(A)-binding protein, Alternative splicing results in multiple transcript variants, Human eIF4G contains three consecutive HEAT domains, The interactions of eIF4G1 with other factors are largely unknown, The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex, The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex, This complex facilitates the recruitment of mRNA to the ribosome, Together with the cap-binding protein eIF4E, [provided by RefSeq], as well as long unstructured regions involved in multiple protein-protein interactions, eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon, some of which are derived from alternative promoter usage, which is a rate-limiting step during the initiation phase of protein synthesis, which may mediate the circularization of mRNA during translation, The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F, eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 4G1_HUMAN, DKFZp686A1451, E4 gamma, E4F, E4G, E4G-I, E4GI, Eukaryotic translation initiation factor 4 gamma 1, e 4 gamma 1, e 4G 1, e 4G1, e-4-gamma 1, e-4G 1, e-4G1, e4G S1238, p-e4G S1238, p-e4G Ser1238, p220, e4G Ser1238
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEIF4G1 (Ser1238)
Short nameEIF4G1 (Ser1238) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEIF4G1 (Ser1238) (Antibody to)
Alternative techniqueantibodies
Identity 3296
Gene EIF4G1
Long gene name eukaryotic translation initiation factor 4 gamma 1
Synonyms gene EIF4G EIF4F
Synonyms gene name 1 , eukaryotic translation initiation factor 4 gamma
Synonyms p220 PARK18
Locus 3q27, 1
Discovery year 1993-06-17
GenBank acession D12686
Entrez gene record 1981
Pubmed identfication 1429670 9372926 21907011
RefSeq identity NM_182917
Classification Parkinson disease associated genes
Havana BLAST/BLAT OTTHUMG00000156784

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