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EIF4G1 (Ser1238) Antibody, Cy5 Conjugated

EIF4G1 (Ser1238) Antibody, Cy5 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, EIF4G1 (Ser1238) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenE4G1 Ser1238
SpecificityThis is a highly specific antibody against E4G1 Ser1238
ModificationPhosphorylation
Modification siteSer1238
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human EIF4G1 around the phosphorylation site of Ser1238
Gene ID number1981
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A domain at its N-terminus can also interact with the poly(A)-binding protein, Alternative splicing results in multiple transcript variants, Human eIF4G contains three consecutive HEAT domains, The interactions of eIF4G1 with other factors are largely unknown, The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex, The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex, This complex facilitates the recruitment of mRNA to the ribosome, Together with the cap-binding protein eIF4E, [provided by RefSeq], as well as long unstructured regions involved in multiple protein-protein interactions, eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon, some of which are derived from alternative promoter usage, which is a rate-limiting step during the initiation phase of protein synthesis, which may mediate the circularization of mRNA during translation, The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F, eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms p220 PARK18
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEIF4G1 (Ser1238) Conjugated
Short name Conjugated, EIF4G1 (Ser1238) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, EIF4G1 (Ser1238) (Antibody to)
Alternative techniqueantibodies
Identity 3296
Gene EIF4G1
Long gene name eukaryotic translation initiation factor 4 gamma 1
Synonyms gene EIF4G EIF4F
Synonyms gene name 1 , eukaryotic translation initiation factor 4 gamma
Locus 3q27, 1
Discovery year 1993-06-17
GenBank acession D12686
Entrez gene record 1981
Pubmed identfication 1429670 9372926 21907011
RefSeq identity NM_182917
Classification Parkinson disease associated genes
Havana BLAST/BLAT OTTHUMG00000156784

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