ELAVL1 (224CT6.5.3) Monoclonal Antibody

ELAVL1 (224CT6.5.3) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 211

Size 0.1ml

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Long name	3) Monoclonal Antibody, 5, ELAVL1 (224CT6
Also known as	3) Monoclonal Antibody, 5, ELAVL1 (224CT6
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	ELAVL1
Specificity	This is a highly specific antibody against ELAVL1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Monoclonal
Clone number	224CT6, 3, 5
Source	This ELAVL1 monoclonal antibody is generated from mouse immunized with ELAVL1 recombinant protein
Gene ID number	1994
Swiss Prot	Q15717
Tested Applications	WB
Recommended dilutions	WB(1:1000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	AUUUUA, Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs, Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (PubMed:8626503), Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs (PubMed:8626503, Hence, In the case of the FOS AU-rich element, Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), May also bind with ZNF385A the CCNB1 mRNA (By similarity), PubMed:17632515, PubMed:18285462, PubMed:18285462), PubMed:23519412), With ZNF385A, and AUUUUUA motifs, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A, binds to a core element of 27 nucleotides that contain AUUUA, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity, promoting ESCs differentiation (By similarity), stabilizing them, RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability (PubMed:14517288
Purification method	This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	ELAV-like protein 1, ELAV1, ELAVL1, Hu-antigen R, Hua, MelG, HUR
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About	Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target	3) Monoclonal, 5, ELAVL1 (224CT6
Short name	3) Monoclonal Antibody, 5, ELAVL1 (224CT6
Technique	Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name	3) monoclonal (Antibody to), 5, ELAVL1 (224CT6
Alternative technique	antibodies
Identity	3312
Gene	ELAVL1
Long gene name	ELAV like RNA binding protein 1
Synonyms gene	HUR
Synonyms gene name	Drosophila)-like 1 (Hu antigen R) , ELAV (embryonic lethal, abnormal vision
Synonyms	HuR Hua MelG
Synonyms name	abnormal vision, drosophila, embryonic lethal, homolog-like 1 Hu antigen R
Locus	19p13, 2
Discovery year	1996-08-12
GenBank acession	U38175
Entrez gene record	1994
Pubmed identfication	8626503 9003489
RefSeq identity	NM_001419
Classification	RNA binding motif containing
Havana BLAST/BLAT	OTTHUMG00000182470

ELAVL1 (224CT6.5.3) Monoclonal Antibody

ELAVL1 (224CT6.5.3) Monoclonal Antibody size: 0.1ml 211

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