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ELAVL2 + ELAVL4 Antibody

ELAVL2 + ELAVL4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameELAVL2 + ELAVL4 Primary Polyclonal Antibody
Also known asELAVL2 + ELAVL4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenELAVL2 + ELAVL4
SpecificityThis is a highly specific antibody against ELAVL2 + ELAVL4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range70-120/359
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ELAVL2
Gene ID number19931996
Swiss ProtP25378, Q12926
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation, An additional mammalian homolog, Characteristically, Elav, Elav proteins function within the nucleus, HuD and Hel-N1, HuR, Several mammalian Elav-like proteins, When Elav-like proteins associate with these ARE sites this degradation is inhibited, a Drosophila protein and the first described member, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, are also expressed in postmitotic neurons, designated HuC, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance, is ubiquitously expressed and is also overexpressed in a wide variety of tumors, leading to an increased stability of the corresponding transcript, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites, which is also designated HuA, The Elav-like genes encode for a family of RNA-binding proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ELAV like protein 2, ELAV like protein 4, ELAV2_HUMAN, ELAV4_HUMAN, ELAVL 2, ELAVL 4, HELN1, HUB, HUD, Hu antigen B, Hu antigen D, ELAV like 4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetELAVL2 + ELAVL4
Short nameELAVL2 + ELAVL4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameELAVL2 and ELAVL4 (Antibody to)
Alternative techniqueantibodies
Identity 3315
Gene ELAVL4
Long gene name ELAV like RNA binding protein 4
Synonyms gene HUD
Synonyms gene name Drosophila)-like 4 (Hu antigen D) ELAV (embryonic lethal, Drosophila)-like 4 ELAV like neuron-specific RNA binding protein 4 , ELAV (embryonic lethal, abnormal vision, abnormal vision
Synonyms PNEM
Synonyms name Hu antigen D
Locus 1p33-p32, 3
Discovery year 1993-07-12
GenBank acession AY033998
Entrez gene record 1996
Pubmed identfication 8222755
RefSeq identity NM_021952
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000007877

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