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ELAVL2/HUB Antibody

ELAVL2/HUB Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameELAVL2/HUB Primary Polyclonal Antibody
Also known asELAVL2/HUB PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenELAVL2/HUB
SpecificityThis is a highly specific antibody against ELAVL2/HUB
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ELAVL2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation, An additional mammalian homolog, Characteristically, Elav, Elav proteins function within the nucleus, HuD and Hel-N1, HuR, Several mammalian Elav-like proteins, When Elav-like proteins associate with these ARE sites this degradation is inhibited, a Drosophila protein and the first described member, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, are also expressed in postmitotic neurons, designated HuC, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance, is ubiquitously expressed and is also overexpressed in a wide variety of tumors, leading to an increased stability of the corresponding transcript, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites, which is also designated HuA, The Elav-like genes encode for a family of RNA-binding proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ELAV like Protein 2, ELAV-like neuronal protein 1, ELAV-like protein 2, ELAV2_HUMAN, ELAVL2, HEL-N1, HELN1, HU Antigen B, HUB, Hu-antigen B, Nervous System Specic RNA Binding Protein MelN1, Nervous system-specic RNA-binding protein Hel-N1, ELAV like Neuronal Protein 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetELAVL2/HUB
Short nameELAVL2/HUB Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameELAVL2/HUB (Antibody to)
Alternative techniqueantibodies
Identity 3313
Gene ELAVL2
Long gene name ELAV like RNA binding protein 2
Synonyms gene name Drosophila)-like 2 (Hu antigen B) ELAV like neuron-specific RNA binding protein 2 , Drosophila)-like 2 ELAV (embryonic lethal, ELAV (embryonic lethal, abnormal vision, abnormal vision
Synonyms HuB HEL-N1
Synonyms name Hu antigen B
Locus 9p21, 3
Discovery year 1996-11-15
GenBank acession BC030692
Entrez gene record 1993
Pubmed identfication 8812435
RefSeq identity NM_004432
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000019700

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