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ELAVL2/HUB Antibody, Cy5 Conjugated

ELAVL2/HUB Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, ELAVL2/HUB Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenELAVL2/HUB
SpecificityThis is a highly specific antibody against ELAVL2/HUB
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ELAVL2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ARE sites target mRNA for rapid degradation and thereby regulate the expression levels of genes involved in cell growth and differentiation, An additional mammalian homolog, Characteristically, Elav, Elav proteins function within the nucleus, HuD and Hel-N1, HuR, Several mammalian Elav-like proteins, When Elav-like proteins associate with these ARE sites this degradation is inhibited, a Drosophila protein and the first described member, and they are shuttled between the nucleus and cytoplasm by a nuclear export signal, are also expressed in postmitotic neurons, designated HuC, is expressed immediately after neuroblastic differentiation into neurons and is necessary for neuronal differentiation and maintenance, is ubiquitously expressed and is also overexpressed in a wide variety of tumors, leading to an increased stability of the corresponding transcript, these homologs all contain three RNA recognition motifs (RRM) and they specifically bind to AU-rich elements (ARE) in the 3'-untranslated region of mRNAs transcripts, which is a regulatory feature of the Elav-like proteins as it limits their accessibility to ARE sites, which is also designated HuA, The Elav-like genes encode for a family of RNA-binding proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms HuB HEL-N1
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetELAVL2/HUB Conjugated
Short name Conjugated, ELAVL2/HUB Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, ELAVL2/HUB (Antibody to)
Alternative techniqueantibodies
Identity 3313
Gene ELAVL2
Long gene name ELAV like RNA binding protein 2
Synonyms gene name Drosophila)-like 2 (Hu antigen B) ELAV like neuron-specific RNA binding protein 2 , Drosophila)-like 2 ELAV (embryonic lethal, ELAV (embryonic lethal, abnormal vision, abnormal vision
Synonyms name Hu antigen B
Locus 9p21, 3
Discovery year 1996-11-15
GenBank acession BC030692
Entrez gene record 1993
Pubmed identfication 8812435
RefSeq identity NM_004432
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000019700

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