Name : ELL3 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6046862210
| Long name | Biotin Conjugated, ELL3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ELL3 |
| Specificity | This is a highly specific antibody against ELL3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ELL3 |
| Gene ID number | 80237 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | ELL (11-19 lysine-rich leukemia protein), ELL is abundantly expressed in peripheral blood leukocytes, ELL3 is a 397 amino acid nuclear protein that functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II, ELL3 is exclusively expressed in testis, Elongation is thought to be a critical stage for the regulation of gene expression, It is also thought to regulate cellular proliferation, This is a multistep process, Though similar to ELL and ELL2, also designated MEN, brain, called the transcription cycle, clearance, elongation and termination, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II, heart, kidney, liver and ovary, lung, placenta and testis, promoter, skeletal muscle, that includes five stages: preinitiation, thymus, with lower expression in spleen, Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FLJ22637 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ELL3 Conjugated |
| Short name | Conjugated, ELL3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, ELL3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 23113 |
| Gene | ELL3 |
| Long gene name | elongation factor for RNA polymerase II 3 |
| Synonyms gene name | elongation factor RNA polymerase II-like 3 |
| Locus | 15q15, 3 |
| Discovery year | 2003-09-17 |
| GenBank acession | AF276512 |
| Entrez gene record | 80237 |
| Pubmed identfication | 10882741 |
| RefSeq identity | NM_025165 |
| Classification | Super elongation complex |
| Havana BLAST/BLAT | OTTHUMG00000059936 |