Name : ELMO1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4994800591
| Long name | FITC Conjugated, ELMO1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ELMO1 |
| Specificity | This is a highly specific antibody against ELMO1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ELMO |
| Gene ID number | 9844 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases, It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1, ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | KIAA0281 CED12 ELMO-1 CED-12 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ELMO1 Conjugated |
| Short name | FITC Conjugated, ELMO1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, engulfment and cellular motility 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CED-12 and CED12 and ELMO-1, ELMO1 and IDBG-12649 and ENSG00000155849 and 9844, ELMO1 and IDBG-633074 and ENSBTAG00000003490 and 509821, Elmo1 and IDBG-132929 and ENSMUSG00000041112 and 140580, Plasma membranes, SH3 domain binding, engulfment and biological process this GO :0006915 and apoptotic process and biological process this GO :0006928 and cellular component movement and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016601 and Rac protein signal transduction and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0030029 and actin filament-based process and biological process this GO :0030036 and actin cytoskeleton organization and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0045087 and innate immune response and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process, this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0006911 and pha this GO cytosis, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, engulfment and cell motility 1 |
| Identity | 16286 |
| Gene | ELMO1 |
| Long gene name | engulfment and cell motility 1 |
| Synonyms gene name | C, elegans) , engulfment and cell motility 1 (ced-12 homolog |
| Locus | 7p14, 1 , 2-p14 |
| Discovery year | 2001-12-13 |
| GenBank acession | AF398885 |
| Entrez gene record | 9844 |
| Pubmed identfication | 11595183 |
| RefSeq identity | NM_130442 |
| Classification | Engulfment and cell motility proteins |
| Havana BLAST/BLAT | OTTHUMG00000023701 |