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Emerin Antibody

Emerin Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEmerin Primary Polyclonal Antibody
Also known asEmerin PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEmerin
SpecificityThis is a highly specific antibody against Emerin
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Emerin
Gene ID number2010
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway, Association of EMD with the viral DNA requires the presence of BAF and viral integrase, EMD and BAF are cooperative cofactors of HIV-1 infection, Inhibits beta-catenin activity by preventing its accumulation in the nucleus, Links centrosomes to the nuclear envelope via a microtubule association, Required for proper localization of non-farnesylated prelamin-A/C, Skeletal muscle, Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments, The association of viral DNA with chromatin requires the presence of BAF and EMD, colon, heart, ovary and pancreas, testis, Stabilizes and promotes the formation of a nuclear actin cortical network, Tissue specificity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EMD, EMD_HUMAN, Emerin, Emery Dreuss muscular dystrophy, STA, EDMD
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetEmerin
Short nameEmerin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEmerin (Antibody to)
Alternative techniqueantibodies
Identity 3331
Gene EMD
Long gene name emerin
Synonyms gene name Emery-Dreifuss muscular dystrophy
Synonyms STA LEMD5
Synonyms name LEM domain containing 5
Locus Xq28
Discovery year 2001-06-22
GenBank acession X82434
Entrez gene record 2010
Classification LEM domain containing
Havana BLAST/BLAT OTTHUMG00000033186
Locus Specific Databases Leiden Muscular Dystrophy Pages UMD Locus Specific Databases Leiden Muscular Dystrophy pages Mental Retardation database LRG_745

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