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EML4 Antibody, FITC Conjugated

EML4 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, EML4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEML4
SpecificityThis is a highly specific antibody against EML4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human EML4/C2orf180
Gene ID number27436
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background C2orf2 or ROPP120, Due to a chromosomal inversion with chromosome 2p, ELP120, EML4 (Echinoderm microtubule-associated protein-like 4), EML4 is thought to modify the assembly dynamics of microtubules, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules, Expressed at high levels during mitosis, also known as EMAPL4, cell motility, is a 981 amino acid cytoplasmic protein that contains nine WD repeats, producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer, specifically altering microtubules to become longer and more flexible, spindle formation and chromosome movements, Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ROPP120 ELP120
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEML4 Conjugated
Short name FITC Conjugated, EML4 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, EML4 (Antibody to)
Alternative techniqueantibodies
Identity 1316
Gene EML4
Long gene name echinoderm microtubule associated protein like 4
Synonyms gene C2orf2
Locus 2p21
Discovery year 2000-01-31
GenBank acession AF177377
Entrez gene record 27436
RefSeq identity NM_019063
Classification WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000128603

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