Name : EMP1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9851170955
| Long name | Biotin Conjugated, EMP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | EMP1 |
| Specificity | This is a highly specific antibody against EMP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 105-135/160 |
| Subcellular location | Cell membrane |
| Source | KLH conjugated synthetic peptide derived from mouse Emp1 |
| Gene ID number | 13730 |
| Swiss Prot | P47801 |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Rat, Mouse |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing, EMP-1 is very similar in structure to its close relative, EMP-1 may also be an important regulator in cell communication, EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer, It is a member of a small family of epithelial membrane proteins, It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border, Peripheral Myelin Protein 22 (PMP22), S phase is arrested and G1 phase is prolonged in esophogeal cancer cells, When EMP-1 is overexpressed, and adhesion, cell proliferation is inhibited, signaling, Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | TMP CL-20 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | EMP1 Conjugated |
| Short name | Conjugated, EMP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, EMP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3333 |
| Gene | EMP1 |
| Long gene name | epithelial membrane protein 1 |
| Locus | 12p13, 1 |
| Discovery year | 1997-12-05 |
| GenBank acession | U43916 |
| Entrez gene record | 2012 |
| Pubmed identfication | 8996089 9126480 |
| RefSeq identity | NM_001423 |
| Havana BLAST/BLAT | OTTHUMG00000168775 |