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EMP1 Antibody, Biotin Conjugated

EMP1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, EMP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEMP1
SpecificityThis is a highly specific antibody against EMP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range105-135/160
Subcellular locationCell membrane
SourceKLH conjugated synthetic peptide derived from mouse Emp1
Gene ID number13730
Swiss ProtP47801
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Rat, Mouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing, EMP-1 is very similar in structure to its close relative, EMP-1 may also be an important regulator in cell communication, EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer, It is a member of a small family of epithelial membrane proteins, It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border, Peripheral Myelin Protein 22 (PMP22), S phase is arrested and G1 phase is prolonged in esophogeal cancer cells, When EMP-1 is overexpressed, and adhesion, cell proliferation is inhibited, signaling, Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms TMP CL-20
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetEMP1 Conjugated
Short name Conjugated, EMP1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, EMP1 (Antibody to)
Alternative techniqueantibodies
Identity 3333
Gene EMP1
Long gene name epithelial membrane protein 1
Locus 12p13, 1
Discovery year 1997-12-05
GenBank acession U43916
Entrez gene record 2012
Pubmed identfication 8996089 9126480
RefSeq identity NM_001423
Havana BLAST/BLAT OTTHUMG00000168775

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