Name : EMP1 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8902394470
| Long name | FITC Conjugated, EMP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | EMP1 |
| Specificity | This is a highly specific antibody against EMP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 105-135/160 |
| Subcellular location | Cell membrane |
| Source | KLH conjugated synthetic peptide derived from mouse Emp1 |
| Gene ID number | 13730 |
| Swiss Prot | P47801 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Mouse |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing, EMP-1 is very similar in structure to its close relative, EMP-1 may also be an important regulator in cell communication, EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer, It is a member of a small family of epithelial membrane proteins, It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border, Peripheral Myelin Protein 22 (PMP22), S phase is arrested and G1 phase is prolonged in esophogeal cancer cells, When EMP-1 is overexpressed, and adhesion, cell proliferation is inhibited, signaling, Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | TMP CL-20 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | EMP1 Conjugated |
| Short name | FITC Conjugated, EMP1 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, EMP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3333 |
| Gene | EMP1 |
| Long gene name | epithelial membrane protein 1 |
| Locus | 12p13, 1 |
| Discovery year | 1997-12-05 |
| GenBank acession | U43916 |
| Entrez gene record | 2012 |
| Pubmed identfication | 8996089 9126480 |
| RefSeq identity | NM_001423 |
| Havana BLAST/BLAT | OTTHUMG00000168775 |