Name : EMR2/CD312 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4753043911
| Long name | EMR2/CD312 Primary Polyclonal Antibody |
| Also known as | EMR2/CD312 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | EMR2/CD312 |
| Specificity | This is a highly specific antibody against EMR2/CD312 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EMR2/CD312 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Derived from the processing of a single polypeptide, EGF-TM7 receptors are a family of class B, EGF-TM7 receptors interact with cellular ligands such as CD55 and chondroitin sulfate, EMR2 is a heptahelical molecule predominantly expressed on cells of the immune system such as leukocytes, EMR2 is a member of the EGF-TM7 receptor subfamily, EMR2 is proteo-lytically cleaved into two separate subunits: a seven-transmembrane subunit, G protein-coupled receptors, Through a variable number of N-terminal EGF-like domains, Within the TM7 superfamily, and an extracellular Alpha subunit, seven-span transmembrane (TM7) receptors predominantly expressed by cells of the immune system, the molecular structure and ligand-binding properties of EGF-TM7 receptors are unique, they are expressed at the cell surface as heterodimers consisting of a large extracellular region associated with a TM7 moiety, which includes CD97 and EMR2, The epidermal growth factor (EGF) family constitutes a group of class B |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD 312 antigen, CD312, CD312 antigen, EGF like module EMR2, EGF-like module receptor 2, EGF-like module-containing mucin-like hormone receptor-like 2, EMR2, EMR2_HUMAN, Egf like module containing mucin like hormone receptor like 2, Egf like module containing mucin like hormone receptor like sequence 2, CD 312 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | EMR2/CD312 |
| Short name | EMR2/CD312 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | EMR2/CD312 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3337 |
| Gene | ADGRE2 |
| Long gene name | adhesion G protein-coupled receptor E2 |
| Synonyms gene | EMR2 |
| Synonyms gene name | egf-like module containing, hormone receptor-like 2 , hormone receptor-like sequence 2 egf-like module containing, mucin-like, mucin-like |
| Synonyms | CD312 |
| Locus | 19p13, 12 |
| Discovery year | 2000-03-14 |
| GenBank acession | AF114491 |
| Entrez gene record | 30817 |
| Pubmed identfication | 25713288 |
| Classification | CD molecules Adhesion G protein-coupled receptors, subfamily E |
| Havana BLAST/BLAT | OTTHUMG00000183408 |