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Endoplasmic Reticulum Amyloid Binding Protein Antibody (ERAB)

Endoplasmic Reticulum Amyloid Binding Protein Antibody (ERAB) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEndoplasmic Reticulum Amyloid Binding Protein (ERAB)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB, IHC
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis ERAB antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q6IBS9
PurityAntigen affinity
Description ERAB appears to trigger cell stress induced by the amyloid peptide, In an amyloid beta-abundant environment, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols, unique among this family, Endoplasmic Reticulum Amyloid Binding protein is a member of the family of short chain dehydrogenase/reductases
ImmunogenA portion of amino acids 199-235 from the human protein was used as the immunogen for this ERAB antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the ERAB antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetEndoplasmic Reticulum Amyloid Binding Protein (ERAB)
Short nameEndoplasmic Reticulum Amyloid Binding Protein Antibody (ERAB)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEndoplasmic Reticulum Amyloid Binding Protein (Antibody to) (ERAB)
Alternative techniqueantibodies
Identity 4800
Gene HSD17B10
Long gene name hydroxysteroid 17-beta dehydrogenase 10
Synonyms gene HADH2 MRXS10
Synonyms gene name X-linked, hydroxyacyl-Coenzyme A dehydrogenase, hydroxyacyl-Coenzyme A dehydrogenase, syndromic 10 hydroxysteroid (17-beta) dehydrogenase 10 , type II, type II mental retardation
Synonyms ERAB MHBD 17b-HSD10 ABAD SDR5C1 MRPP2 CAMR
Synonyms name member 1 mitochondrial RNase P subunit 2 , type 10 17b-HSD type 10 17beta-hydroxysteroid dehydrogenase AB-binding alcohol dehydrogenase short chain dehydrogenase/reductase family 5C
Locus Xp11, 22
Discovery year 1997-04-25
GenBank acession U96132
Entrez gene record 3028
Pubmed identfication 9338779 16899120 19027726 18984158 17236142
RefSeq identity NM_004493
Classification X-linked mental retardation Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT OTTHUMG00000021612
Locus Specific Databases Mental Retardation database LRG_450

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