| Long name | ENPP1 Primary Polyclonal Antibody |
| Also known as | ENPP1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ENPP1 |
| Specificity | This is a highly specific antibody against ENPP1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 97-150/925 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ENPP1 |
| Gene ID number | 5167 |
| Swiss Prot | P22413 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Appears to modulate insulin sensitivity and function, CTP, May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, Preferentially hydrolyzes ATP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3', and functions in bone mineralization and soft tissue calcification, and the regulation of purinergic signaling, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, plays a role in regulating pyrophosphate levels, thereby preventing further growth of these crystals, 5'-cAMP to AMP, By generating PPi |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ARHR2, COLED, E-NPP 1, ENPP1, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Membrane component chromosome 6 surface marker 1, NPP1, NPPS, PC-1, PC1, PCA1, PDNP1, Phosphodiesterase I/nucleotide pyrophosphatase 1, Plasma-cell membrane glycoprotein PC-1, M6S1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ENPP1 |
| Short name | ENPP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ectonucleotide pyrophosphatase/phosphodiesterase 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | 3'-phosphoadenosine 5'-phosphosulfate binding, ARHR2 and COLED and M6S1 and NPP1 and NPPS and PC-1 and PCA1 and PDNP1, ENPP1 and IDBG-633303 and ENSBTAG00000021830 and 615535, ENPP1 and IDBG-96591 and ENSG00000197594 and 5167, Enpp1 and IDBG-138688 and ENSMUSG00000037370 and 18605, Extracellular, this GO :0003676 and nucleic acid binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004528 and phosphodiesterase I activity and molecular function this GO :0004551 and nucleotide diphosphatase activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0006200 and ATP catabolic process and biological process this GO :0006766 and vitamin metabolic process and biological process this GO :0006767 and water-soluble vitamin metabolic process and biological process this GO :0006771 and riboflavin metabolic process and biological process this GO :0006796 and phosphate-containing compound metabolic process and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006955 and immune response and biological process this GO :0008152 and metabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009143 and nucleoside triphosphate catabolic process and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016787 and hydrolase activity and molecular function this GO :0030247 and polysaccharide binding and molecular function this GO :0030279 and negative regulation of ossification and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030500 and regulation of bone mineralization and biological process this GO :0030505 and inorganic diphosphate transport and biological process this GO :0030643 and cellular phosphate ion homeostasis and biological process this GO :0030730 and sequestering of triglyceride and biological process this GO :0031214 and biomineral tissue development and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0035529 and NADH pyrophosphatase activity and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045719 and negative regulation of glycogen biosynthetic process and biological process this GO :0046325 and negative regulation of glucose import and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046849 and bone remodeling and biological process this GO :0046872 and metal ion binding and molecular function this GO :0047429 and nucleoside-triphosphate diphosphatase activity and molecular function this GO :0050427 and 3'-phosphoadenosine 5'-phosphosulfate metabolic process and biological process this GO :0050656 and 3'-phosphoadenosine 5'-phosphosulfate binding and molecular function this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, this GO :0003676: nucleic acid binding, this GO :0003676: nucleic acid binding and also this GO :0003824: catalytic activity and also this GO :0004528: phosphodiesterase I activity and also this GO :0004551: nucleotide diphosphatase activity and also this GO :0005044: scavenger receptor activity and also this GO :0005158: insulin receptor binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008270: zinc ion binding and also this GO :0016787: hydrolase activity and also this GO :0030247: polysaccharide binding and also this GO :0035529: NADH pyrophosphatase activity and also this GO :0042803: protein homodimerization activity and also this GO :0046872: metal ion binding and also this GO :0047429: nucleoside-triphosphate diphosphatase activity and also this GO :0050656: 3'-phosphoadenosine 5'-phosphosulfate binding, this GO :0003824: catalytic activity, this GO :0004528: phosphodiesterase I activity, this GO :0004551: nucleotide diphosphatase activity, this GO :0005044: scavenger receptor activity, this GO :0005158: insulin receptor binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008270: zinc ion binding, this GO :0016787: hydrolase activity, this GO :0030247: polysaccharide binding, this GO :0035529: NADH pyrophosphatase activity, this GO :0042803: protein homodimerization activity, this GO :0046872: metal ion binding, this GO :0047429: nucleoside-triphosphate diphosphatase activity, this GO :0050656: 3'-phosphoadenosine 5'-phosphosulfate binding, ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| Identity | 3356 |
| Gene | ENPP1 |
| Long gene name | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| Synonyms gene | NPPS M6S1 PDNP1 |
| Synonyms | PC-1 PCA1 |
| Locus | 6q23, 2 |
| Discovery year | 1992-12-08 |
| GenBank acession | M57736 |
| Entrez gene record | 5167 |
| Pubmed identfication | 1315502 |
| Havana BLAST/BLAT | OTTHUMG00000015572 |
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