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ENSA/ARPP-19 Antibody, Biotin Conjugated

ENSA/ARPP-19 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, ENSA/ARPP-19 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenENSA/ARPP-19
SpecificityThis is a highly specific antibody against ENSA/ARPP-19
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ENSA/ARPP-19
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ENSA/ARPP-19, ENSA/ARPP-19 is an endogenous regulator of the Î, ENSA/ARPP-19 is encoded by a gene located on human chromosome 1q21, ENSA/ARPP-19 is phosphorylated by PKA and exists as eight alternatively spliced isoforms, It is suggested that ENSA/ARPP-19 expression is decreased in brains of both Alzheimer's disease (AD) and Down's syndrome patients, Widely expressed with high levels in skeletal muscle and brain and lower levels in pancreas, also known as ARPP-19e, cells, is a 121 amino acid protein that localizes to the cytoplasm and belongs to the endosulfine family, ², ², -cell K(ATP) channels and reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor thereby stimulating insulin secretion by pancreatic Î, 3, Sulfonylureas are a class of drugs commonly used in the management of noninsulin-dependent diabetes mellitus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MGC4319 MGC8394 MGC78563 ARPP-19e
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetENSA/ARPP-19 Conjugated
Short name Conjugated, ENSA/ARPP-19 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ENSA/ARPP-19 (Antibody to)
Alternative techniqueantibodies
Identity 3360
Gene ENSA
Long gene name endosulfine alpha
Locus 1q21, 3
Discovery year 1998-08-21
GenBank acession X99906
Entrez gene record 2029
Pubmed identfication 9653196
RefSeq identity NM_207042
Havana BLAST/BLAT OTTHUMG00000035004

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