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Eotaxin Antibody / CCL11

Eotaxin Antibody / CCL11 size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEotaxin / CCL11
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutions1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0
NotesOptimal dilution of the CCL11 antibody should be determined by the researcher
Intented useThis CCL11 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P51671
PurityAntigen affinity
Description CCR3 and CCR5, Chemokine receptors for which Eotaxin is a ligand include CCR2, Eotaxin selectively recruits eosinophils by inducing their chemotaxis, However, The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor, The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12, also known as Eotaxin, and therefore, is a small cytokine belonging to the CC chemokine family, is implicated in allergic responses, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3, CCL11 (Chemokine (C-C motif) ligand 11)
ImmunogenAmino acids 24-97 of human Eotaxin/CCL11 were used as the immunogen for the CCL11 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCL11 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetEotaxin / CCL11
Short nameEotaxin Antibody / CCL11
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEotaxin (Antibody to) / chemokine (C-C motif) ligand 11
Alternative techniqueantibodies
Alternative to gene target CCL11 and IDBG-40645 and ENSG00000172156 and 6356, CCL11 and IDBG-630948 and ENSBTAG00000004129 and 404072, Ccl11 and IDBG-204519 and ENSMUSG00000020676 and 20292, Extracellular, SCYA11, chemokine activity, this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0002551 and mast cell chemotaxis and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008360 and regulation of cell shape and biological process this GO :0009314 and response to radiation and biological process this GO :0009615 and response to virus and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0048245 and eosinophil chemotaxis and biological process this GO :0060444 and branching involved in mammary gland duct morphogenesis and biological process this GO :0060763 and mammary duct terminal end bud growth and biological process this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0070670 and response to interleukin-4 and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008009: chemokine activity, this GO :0008009: chemokine activity, chemokine (C-C motif) ligand 11
Identity 10610
Gene CCL11
Long gene name C-C motif chemokine ligand 11
Synonyms gene SCYA11
Synonyms gene name member 11 (eotaxin) chemokine (C-C motif) ligand 11 , small inducible cytokine subfamily A (Cys-Cys)
Synonyms eotaxin MGC22554
Synonyms name eotaxin-1
Locus 17q12
Discovery year 1996-04-24
GenBank acession AB063614
Entrez gene record 6356
Pubmed identfication 9169149
RefSeq identity NM_002986
Classification Endogenous ligands Chemokine ligands
Havana BLAST/BLAT OTTHUMG00000132884

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