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Epac1 Antibody, ALEXA FLUOR 594

Epac1 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, Epac1 Polyclonal Antibody
Also known asAnti-Epac1 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEpac1
SpecificityThis is a highly specific antibody against Epac1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Epac1
Gene ID Number1019
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Both proteins are multidomain proteins containing an autoinhibitory cAMP-binding domain that inhibits the catalytic region and a DEP domain (dishevelled, EPAC1 mRNA is broadly expressed, EPAC2 has an additional cAMP-binding site in its N-terminus that binds cAMP with low affinity, Egl-10 and pleckstrin homology domain) targeting the membrane anchors, Epac 1 and Epac 2 also interact with light chain 2 (LC2) or MAP1A that serves as a scaffolding structure to stabilize the signal transduction complex, Epac1 and Epac 2, The Epac 1-selective were generated against unique antigenic sequences form near N-terminus and between RasGEFN and Ras GEF domains, The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade, The to Epac 1are affinity purified over immobilized antigen based chromatography, There are 2 members of the Epac family, kidney and certain brain regions, ovary, whereas expression of EPAC2 mRNA appears to be restricted to the brain and adrenal glands, with particularly high levels occurring in the thyroid, The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms CAMP GEFI, CAMPGEFI, CGEF 1, CGEF1, EPA1, EPAC, EPAC1, Epac 1, Exchange factor directly activated by cAMP 1, Exchange protein directly activated by cAMP 1, MGC21410, RAP guanine nucleotide exchange factor, RAP guanine nucleotide exchange factor 3, RAPGEF3, Rap guanine nucleotide exchange factor GEF 3, Rap1 guanine nucleotide exchange factor directly activated by cAMP, cAMP regulated guanine nucleotide exchange factor I, bcm910
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetEpac1
Short nameEpac1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Epac1 (Antibody to)
Alternative techniqueantibodies

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