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Eph receptor A5 Antibody

Eph receptor A5 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEph receptor A5 Primary Polyclonal Antibody
Also known asEph receptor A5 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEph receptor A5
SpecificityThis is a highly specific antibody against Eph receptor A5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range468-500/1037
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EphA5/Eph receptor A5
Gene ID number2044
Swiss ProtP54756
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5, Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, In addition to its function in the nervous system, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis, entorhino-hippocampal and hippocamposeptal pathways, leading to contact-dependent bidirectional signaling into neighboring cells, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity), Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BSK, Brain-specific kinase, CEK7, EHK-1, EHK1, EPH homology kinase 1, EPH-like kinase 7, EPHA5, Ephrin type-A receptor 5, HEK7, TYRO4, EK7
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEph receptor A5
Short nameEph receptor A5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEph receptor A5 (Antibody to)
Alternative techniqueantibodies
Identity 3389
Gene EPHA5
Long gene name EPH receptor A5
Synonyms gene name EphA5
Synonyms Hek7 TYRO4 CEK7 EHK1
Locus 4q13, 1-q13, 2
Discovery year 1997-10-10
GenBank acession L36644
Entrez gene record 2044
Pubmed identfication 9267020 7528718
RefSeq identity NM_004439
Classification Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors
Havana BLAST/BLAT OTTHUMG00000129273

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