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Eph receptor A7 Antibody, ALEXA FLUOR 647

Eph receptor A7 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, Eph receptor A7 Polyclonal Antibody
Also known asAnti-EphA7 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEphA7
SpecificityThis is a highly specific antibody against EphA7
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range203-253/998
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EphA7
Gene ID Number2045
Swiss ProtQ15375
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion, Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7, May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, leading to contact-dependent bidirectional signaling into neighboring cells, Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms Hek11
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Eph receptor A7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEph receptor A7
Short nameEph receptor A7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, Eph receptor A7 (Antibody to)
Alternative techniqueantibodies
Identity 3390
Gene EPHA7
Long gene name EPH receptor A7
Synonyms gene name EphA7
Locus 6q16, 1
Discovery year 1997-10-10
GenBank acession L36642
Entrez gene record 2045
Pubmed identfication 9267020
Classification Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors
Havana BLAST/BLAT OTTHUMG00000015228

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