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Eph receptor B1 (Tyr928) Antibody

Eph receptor B1 (Tyr928) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameEph receptor B1 (Tyr928) Antibody
Also known asEph receptor B1 (Tyr928) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEph receptor B1 Tyr928
SpecificityThis is a highly specific antibody against Eph receptor B1 Tyr928
Modification(s)Phosphorylation
Modification site(s)Tyr928
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range910-950/984
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr928
Gene ID number2047
Swiss ProtP54762
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cognate/functional ephrin ligands for this receptor include EFNB1, During nervous system development, EFNB2 and EFNB3, In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation, In the adult nervous system together with EFNB3, May also regulate angiogenesis, More generally, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, This probably requires repulsive interaction with EFNB2, Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively, leading to contact-dependent bidirectional signaling into neighboring cells, may play a role in targeted cell migration and adhesion, proliferation and polarity of the hippocampus neural progenitors, regulates chemotaxis, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names EK6, EPH tyrosine kinase 2, EPH-like kinase 6, EPHB1, EPHT2, Ephrin type-B receptor 1, Hek6, NET, Neuronally-expressed EPH-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-2, ELK
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEph receptor B1 (Tyr928)
Short nameEph receptor B1 (Tyr928) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameEph receptor B1 (Tyr928) (Antibody to)
Alternative techniqueantibodies

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