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Eph receptor B1 (Tyr928) Antibody, ALEXA FLUOR 647

Eph receptor B1 (Tyr928) Antibody, ALEXA FLUOR 647 size: 100ul 350

Price 350
Size 100ul
Long name ALEXA FLUOR 647 Conjugated, Eph receptor B1 (Tyr928) Antibody
Also known asAnti-Eph receptor B1 Tyr928 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEph receptor B1 Tyr928
SpecificityThis is a highly specific antibody against Eph receptor B1 Tyr928
ModificationPhosphorylation
Modification SiteTyr928
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range910-950/984
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr928
Gene ID Number2047
Swiss ProtP54762
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Cognate/functional ephrin ligands for this receptor include EFNB1, During nervous system development, EFNB2 and EFNB3, In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation, In the adult nervous system together with EFNB3, May also regulate angiogenesis, More generally, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, This probably requires repulsive interaction with EFNB2, Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively, leading to contact-dependent bidirectional signaling into neighboring cells, may play a role in targeted cell migration and adhesion, proliferation and polarity of the hippocampus neural progenitors, regulates chemotaxis, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms EK6, EPH tyrosine kinase 2, EPH-like kinase 6, EPHB1, EPHT2, Ephrin type-B receptor 1, Hek6, NET, Neuronally-expressed EPH-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-2, ELK
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Eph receptor B1 (Tyr928) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEph receptor B1 (Tyr928)
Short nameEph receptor B1 (Tyr928) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, Eph receptor B1 (Tyr928) (Antibody to)
Alternative techniqueantibodies

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