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Eph receptor B1 (Tyr928) Antibody, FITC Conjugated

Eph receptor B1 (Tyr928) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Eph receptor B1 (Tyr928) Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenEph receptor B1 Tyr928
SpecificityThis is a highly specific antibody against Eph receptor B1 Tyr928
ModificationPhosphorylation
Modification siteTyr928
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range910-950/984
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr928
Gene ID number2047
Swiss ProtP54762
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Cognate/functional ephrin ligands for this receptor include EFNB1, During nervous system development, EFNB2 and EFNB3, In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation, In the adult nervous system together with EFNB3, May also regulate angiogenesis, More generally, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, This probably requires repulsive interaction with EFNB2, Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively, leading to contact-dependent bidirectional signaling into neighboring cells, may play a role in targeted cell migration and adhesion, proliferation and polarity of the hippocampus neural progenitors, regulates chemotaxis, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms EK6, EPH tyrosine kinase 2, EPH-like kinase 6, EPHB1, EPHT2, Ephrin type-B receptor 1, Hek6, NET, Neuronally-expressed EPH-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-2, ELK
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetEph receptor B1 (Tyr928) Conjugated
Short name FITC Conjugated, Eph receptor B1 (Tyr928) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Eph receptor B1 (Tyr928) (Antibody to)
Alternative techniqueantibodies

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