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EPHA5 (46CT61.6.4) Monoclonal Antibody

EPHA5 (46CT61.6.4) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name4) Monoclonal Antibody, 6, EPHA5 (46CT61
Also known as4) Monoclonal Antibody, 6, EPHA5 (46CT61
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenEPHA5
SpecificityThis is a highly specific antibody against EPHA5
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number4, 46CT61, 6
SourcePurified His-tagged EPHA5 protein(Fragment) was used to produced this monoclonal antibody
Gene ID number2044
Swiss ProtP54756
Tested Applications IHC-P, WB
Recommended dilutions IHC-P(1:10~50), WB(1:1000-2000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5, Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, In addition to its function in the nervous system, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis, entorhino-hippocampal and hippocamposeptal pathways, leading to contact-dependent bidirectional signaling into neighboring cells, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity), Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BSK, Brain-specific kinase, CEK7, EHK-1, EHK1, EPH homology kinase 1, EPH-like kinase 7, EPHA5, Ephrin type-A receptor 5, HEK7, TYRO4, EK7
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target4) Monoclonal, 6, EPHA5 (46CT61
Short name4) Monoclonal Antibody, 6, EPHA5 (46CT61
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name4) monoclonal (Antibody to), 6, EPHA5 (46CT61
Alternative techniqueantibodies
Identity 3389
Gene EPHA5
Long gene name EPH receptor A5
Synonyms gene name EphA5
Synonyms Hek7 TYRO4 CEK7 EHK1
Locus 4q13, 1-q13, 2
Discovery year 1997-10-10
GenBank acession L36644
Entrez gene record 2044
Pubmed identfication 9267020 7528718
RefSeq identity NM_004439
Classification Sterile alpha motif domain containing Fibronectin type III domain containing EPH receptors
Havana BLAST/BLAT OTTHUMG00000129273

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